On the other hand, inhibition of NAD(P)H oxidase with diphenylene iodonium (DPI), xanthine oxidase (XO) with allopurinol, nitric oxide synthase (NOS) with N-nitro-L-arginine (L-NNA) or cyclooxygenase (COX) pathway by mefenamic acid demonstrated zero significant inhibitory effect [32]

On the other hand, inhibition of NAD(P)H oxidase with diphenylene iodonium (DPI), xanthine oxidase (XO) with allopurinol, nitric oxide synthase (NOS) with N-nitro-L-arginine (L-NNA) or…