The ALDH+ cells presented CSC features such as for example higher degrees of SOX2, Nestin and NANOG, formed more sphere-like structures and had higher resistance to 5-FU and cisplatin (Zhi et al

The ALDH+ cells presented CSC features such as for example higher degrees of SOX2, Nestin and NANOG, formed more sphere-like structures and had higher resistance…

After monolayer formation, cells were again trypsinized and plated in 60 mm culture dishes (TPP) at a density of 3 104/ml and cultured until subconfluence

After monolayer formation, cells were again trypsinized and plated in 60 mm culture dishes (TPP) at a density of 3 104/ml and cultured until subconfluence….

The window of normalization in murine models is relatively short and occurs soon after administration of bevacizumab compared with that in humans [29], which may explain several paradoxical findings reported recently and suggest that the schedule and dosing of combination therapies warrant considerable attention

The window of normalization in murine models is relatively short and occurs soon after administration of bevacizumab compared with that in humans [29], which may…